Flock House virus protein B2 suppresses the RNA-mediated interference response by binding double-stranded RNA of almost any size or sequence. The crystal structure of this protein bound to RNA reveals a novel fold that suggests its mechanism of action.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Voinnet, O. Nat. Rev. Genet. 6, 206–220 (2005).
Sontheimer, E.J. & Carthew, R.W. Cell 122, 9–12 (2005).
Lu, R. et al. Nature 436, 1040–1043 (2005).
Li, H., Li, W.X. & Ding, S.W. Science 296, 1319–1321 (2002).
Chao, J.A. et al. Nat. Struct. Mol. Biol. 12, 952–957 (2005).
Silhavy, D. et al. EMBO J. 21, 3070–3080 (2002).
Ye, K., Malinina, L. & Patel, D.J. Nature 426, 874–878 (2003).
Vargason, J.M., Szittya, G., Burgyan, J. & Tanaka Hall, T.M. Cell 115, 799–811 (2003).
Chang, K.Y. & Ramos, A. FEBS J. 272, 2109–2117 (2005).
Lichner, Z., Silhavy, D. & Burgyan, J. J. Gen. Virol. 84, 975–980 (2003).
Sullivan, C.S. & Ganem, D. J. Virol. 79, 7371–7379 (2005).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kieft, J., Pfingsten, J. Weapons in the molecular arms race. Nat Struct Mol Biol 12, 938–939 (2005). https://doi.org/10.1038/nsmb1105-938
Issue Date:
DOI: https://doi.org/10.1038/nsmb1105-938
