Table 3 ROAST differential expression statistics (P-values shown) across the Cancer Genome Atlas ovarian-cancer gene-expression data set for gene sets defined by different histone marks

From: Chromatin H3K27me3/H3K4me3 histone marks define gene sets in high-grade serous ovarian cancer that distinguish malignant, tumour-sustaining and chemo-resistant ovarian tumour cells

Histone mark

Tumour overexpressed, P-values

Tumour downregulated, P-values

Bivalent

1

0.0022

H3K27me3

1

0.0031

H3K4me3

0.0055

1