Fig. 3: NMac1 bound to the C-terminus of the Nm23-H1 in monomer and hexamer101.
From: Activation of Nm23-H1 to suppress breast cancer metastasis via redox regulation
Overlay of differential HDX data of NMac1 binding shows that NMac1 binds to C-terminal region and a peptide (aa 64–75 residue) is located in the boundary between the C-terminal region and adjacent monomer. NMac1 binding, which induces a decreasing hydrogen-deuterium exchange ratio, is presented in dark blue.
