Fig. 3
Independent variants affecting survival: a Forest plot of variables implicated in progression-free survival (left) and overall survival (right). Hazard ratio on the X axis, values <1 confer better prognosis, values >1 confer worse prognosis. For each variable, the confidence interval is a horizontal gray bar and the hazard ratio—referenced to the X-axis—is represented by a black box. b Kaplan–Meier survival curves for two significant instances of interaction found in the study: prognosis for overall survival is significantly worse in case of coexistence of PRDM1 deletions and t(4;14) (left) or PRDM1 deletions and BIRC2/3 deletions (right) than with either variable alone
