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Acknowledgements
The authors thank Rie Ohmi (Kanazawa University) and Naoya Hosono (Fluidigm Corporation) for their excellent technical assistance. Wild-type Slit1 vector (pENTR2B-hSlit1) was a gift from Professor Kazunobu Sawamoto from Nagoya City University Graduate School of Medical Sciences. This study was supported by a MEXT Grant-in-Aid for Scientific Research (B, 24390243 to SN and Young Scientists (B), 17K16184 to KH).
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KH and SN designed the research, analyzed the data, and wrote the paper. KH, HM, ME, CS, LE, AD, TK, AH, AK, AK, HM, TI, MT and YY performed the experiments. SN was involved in the conceptualization, interpretation of the results, and editing of the paper. All authors critically reviewed the paper and agree with the submission of the final paper.
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Hosokawa, K., Mizumaki, H., Elbadry, M.I. et al. Clonal hematopoiesis by SLIT1-mutated hematopoietic stem cells due to a breakdown of the autocrine loop involving Slit1 in acquired aplastic anemia. Leukemia 33, 2732–2766 (2019). https://doi.org/10.1038/s41375-019-0510-0
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DOI: https://doi.org/10.1038/s41375-019-0510-0
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