Table 1 Patient cohorts in somatic variant analysis.

From: Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia

Dataset

Number of subjects

Purpose

Immunogene panel sequencing of immune-mediated AA patients

24

To investigate somatic mutations in T cells

Immunogene panel sequencing of healthy individuals

20

PON for immunogene panel samples and comparison of adjusted mutation burden for AA samples

Skin WES of patients with AA

9

PON for WES samples and immunogene panel samples

CD3+ and CD3− MNC WES of patients with AA [13]

37

To compare CH derived mutations with somatic mutations seen in T cells

  1. AA aplastic anemia, PON panel of normals, WES whole-exome sequencing, MNC mononuclear cell, CH clonal hematopoiesis.
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