Fig. 8

Effect of CS exposure and BMP-6 deficiency on iron levels in serum and lung tissue. Quantification of the iron concentration in serum (a) and lung homogenates (b) of WT and BMP-6 KO mice exposed to air or CS for 4 weeks. Data are expressed as mean ± SEM (n = 8−12 animals/group; **P < 0.01, ***P < 0.001). c−f Representative photomicrographs of the Prussian blue staining on lung sections of WT and BMP-6 KO mice exposed to air or CS for 4 weeks. Iron deposition is colored in blue and indicated by arrows. Data shown are representative of two independent experiments. g TBARS concentration in lung tissue of WT and BMP-6 KO mice upon 4 weeks exposure to air or CS