Fig. 1: HRMS is more informative and can capture increase in monoclonal light chain earlier than standard methods. | Blood Cancer Journal

Fig. 1: HRMS is more informative and can capture increase in monoclonal light chain earlier than standard methods.

From: Sensitive multiple myeloma disease monitoring by mass spectrometry

Fig. 1

A SPEP, SIFE, HRMS, and sFLC results for subject 122. B HRMS profiles for subject 122 showing detectable monoclonal light chain peak at 22,470.6 ± 1.5 Da in all the time points. The additional peaks in 25,000 mass region represent glycosylated heavy chains at ½ mass based on the difference between the adjacent peaks, which is 81 Da or ½ mass of hexose residue (162 Da). C SPEP, SIFE, HRMS, and sFLC results for subject 116.

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