Table 2 Adverse events according to Common Terminology Criteria for Adverse Events (CTCAE) v3.0
| Â | All grades | Grade 3 or 4 |
|---|---|---|
Adverse event | n (%) | n (%) |
Stomatitis/oral mucositis | 17 (63%) | 2 (7%) |
Pain | 16 (59%) | 4 (15%) |
Rash | 14 (52%) | 1 (4%) |
Nausea | 12 (44%) | 0 (0%) |
Diarrhoea | 12 (44%) | 1 (4%) |
Infections | 11 (41%) | 7 (26%) |
Fatigue | 10 (37%) | 1 (4%) |
Cough | 9 (33%) | 0 (0%) |
Anorexia | 8 (30%) | 1 (4%) |
Vomiting | 8 (30%) | 0 (0%) |
Pruritus | 7 (26%) | 0 (0%) |
Oedema | 7 (26%) | 0 (0%) |
Hyperglycaemia | 6 (22%) | 3 (11%) |
Weight loss | 6 (22%) | 0 (0%) |
Epistaxis | 6 (22%) | 0 (0%) |
Anaemia | 5 (19%) | 3 (11%) |
Hypercholesterolaemia | 5 (19%) | 0 (0%) |
Hypokalaemia | 5 (19%) | 1 (4%) |
Taste alteration | 4 (15%) | 0 (0%) |
Pneumonitis | 4 (15%) | 1 (4%) |
Dry skin | 4 (15%) | 0 (0%) |
Nail changes | 4 (15%) | 0 (0%) |
Insomnia | 4 (15%) | 0 (0%) |
Constipation | 3 (11%) | 1 (4%) |
Headache | 3 (11%) | 0 (0%) |
Neutropenia | 2 (7%) | 0 (0%) |
Thrombocytopenia | 2 (7%) | 1 (4%) |
Flu-like syndrome | 2 (7%) | 0 (0%) |
Thromboembolism | 2 (7%) | 2 (7%) |
Ocular toxicity | 2 (7%) | 0 (0%) |
