Fig. 6: The effect of interaction of IL22RA1 with miR-760 and miR-215-3p on the migration and proliferation of Tenon’s capsule fibroblasts and fibrosis-related proteins. | Cell Death & Disease

Fig. 6: The effect of interaction of IL22RA1 with miR-760 and miR-215-3p on the migration and proliferation of Tenon’s capsule fibroblasts and fibrosis-related proteins.

From: LncRNA NR_003923 promotes cell proliferation, migration, fibrosis, and autophagy via the miR-760/miR-215-3p/IL22RA1 axis in human Tenon’s capsule fibroblasts

Fig. 6

a, b MiR-760 and miR-215-3p reversed the increase in cell migration induced by IL22RA1. c MiR-760 and miR-215-3p reversed the cell proliferation induced by IL22RA1. *p < 0.05 vs control. #p < 0.05 vs TGFβ + NC, $p < 0.05 vs TGF-β + IL22RA1. d–f Expression of E-cadherin, α-SMA, β-catenin, and fibronectin in IL22RA1 treated cells were recovered by transfection of miR-760 and miR-215-3p. *p < 0.05 vs control. #p < 0.05 vs TGFβ + NC, $p < 0.05 vs TGF-β + IL22RA1. Magnification, ×400

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