Fig. 5: BP-1-102 regulated autophagy-related proteins expression in AAA tissues. | Cell Death & Disease

Fig. 5: BP-1-102 regulated autophagy-related proteins expression in AAA tissues.

From: A novel STAT3 inhibitor attenuates angiotensin II-induced abdominal aortic aneurysm progression in mice through modulating vascular inflammation and autophagy

Fig. 5

a Autophagy and apoptosis related proteins expression in AAA tissue were evaluated with western blotting. LC3, Bcl-xL, and Bcl-2 expressions were evaluated in AngII+ BP-1-102+ group (AngII+BP+) and compared with AngII+ group at indicated time points. b Relative protein levels of LC3B, Bcl-xL, and Bcl-2 were determined by normalized with β-actin expression at indicated time points. Levels of LC3B, Bcl-xL, and Bcl-2 in AngII+ BP-1-102+ group (AngII+BP+, blue column) were compared with that of AngII+ group (red column). Saline treated group was used as control (green column). The results were presented as mean ± standard deviation (SD). n = 8. *P < 0.01 vs. AngII+ group (two-way ANOVA followed by Tukey’s test). NS indicates non-significant differences compared with AngII+ group.

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