Fig. 1: LncRNA ZNF674-AS1 is down-regulated in GCs from patients with bPOI and correlates with poor ovary reserve.
From: LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA
A The expression level of ZNF674-AS1 was validated by qRT-PCR in GCs from patients with bPOI (n = 33) and controls (n = 41). Ct values were normalized to GAPDH. *p < 0.05, by two-tailed Student’s t test. B The correlation between the expression level of ZNF674-AS1 in GCs and the serum concentration of estradiol from patients with bPOI (n = 33) was analyzed by Pearson correlation analysis. C The correlation between the expression level of ZNF674-AS1 in GCs and the serum concentration of estradiol, AMH, FSH from all participants (n = 74) was analyzed by Pearson correlation analysis. D Schematic representation of localization of ZNF674-AS1 in chromosome X.
