Fig. 3: NR4A1 upregulates MKP7 expression. | Cell Death Discovery

Fig. 3: NR4A1 upregulates MKP7 expression.

From: NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving

Fig. 3

A The relative mRNA levels of MKP2 and MKP7 in NC and OV cells were determined with qPCR. B and C The relative MKP2 and MKP7 protein levels in both OV and NC cells were determined with Western Blotting. D The protein levels of MKP7 and NR4A1 in response to 100 μM H2O2 in NC cells. E–H The protein levels of MKP7 in response to 100 μM H2O2 and 0.5 μM TG at various time points in both OV and NC cells. The data represented the means of three independent experiments, *P < 0.05, **P < 0.01 vs. ns. Error bars were shown as SD values.

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