Fig. 6 | Nature Communications

Fig. 6

From: Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease

Fig. 6

Cellular contributors to cfDNA in sepsis. a Predicted cellular contributions are shown for 14 samples of cfDNA from patients with sepsis. Cell types present at <1% were included in “Other”. b Pie charts representing predicted distribution of cell types contributing to cfDNA of two of the sepsis patients. c Predicted levels of hepatocyte cfDNA compared to serum levels of alanine aminotransferase (ALT), a standard biomarker for hepatocyte damage (Pearsons’s r = 0.93, p-value ≤ 4e−7). Error bars: SD, as estimated using Bootstrapping

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