Table 1 Nanopore sequencing data sets used to evaluate DeepMod

From: Detection of DNA base modifications by deep recurrent neural network on Oxford Nanopore sequencing data

Genome

Data set name

Motif

# reads

Coverage

Metha

Reference

Escherichia coli

UMR

NAd

111,238

110X

Negb

Simpson et al. 4

CG_MsssI

CGc

69,899

67X

5mC

 

CG_SssI

CGc

8679

19X

5mC

 

CG_MpeI

CGc

23,593

39X

5mC

 

GCGC_HhaI

GCGCc

18,180

50X

5mC

 

gaAttc_EcoRI

GAATTCc

16,661

27X

6mA

Stoiber et al. 3

gAtc_dam

GATCc

17,557

33X

6mA

 

tcgA_TaqI

TCGAc

16,249

22X

6mA

 

Con1

NAd

23,762

34X

Negb

 

Con2

NAd

34,170

40X

Negb

 

Homo sapiens

NA12878

CGc

 

30X

5mC

Jain et al. 31

HX1

CGc

4,827,155

30X

5mC

Current study

Chlamydomonas reinhardtii

C. reinhardtii

NAd

772,817

126X

6mA

Current study

  1. a Methylation types
  2. b Negative control without any modifications
  3. c Underlined nucleotides in motifs were potential modified target.
  4. d No modifications or no motif information