Table 1 Telomerase processivity IC50 values.
From: Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs
Modified dNTP | IC50 μM ± SD |
|---|---|
8-oxo-dATP | 946 ± 49 |
2-OH-dATP | 103 ± 66 |
8-oxo-dGTP | 1690 ± 172 |
ddITP | 61 ± 23 |
AZT-TP | 402 ± 169 |
6-thio-dGTP | 5 ± 2 |
