Intratumoral injection of a hydrogel impregnated with radioisotope-labelled catalase and an immunostimulant, along with systemic immune checkpoint blockade, inhibits tumour growth in mouse models of localized cancer and metastatic cancer.
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Spina, C.S., Drake, C.G. Combined local and systemic attacks. Nat Biomed Eng 2, 564–565 (2018). https://doi.org/10.1038/s41551-018-0277-z
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DOI: https://doi.org/10.1038/s41551-018-0277-z