Enzymatic approaches to synthesize oligosaccharides offer an alternative to chemical syntheses for the production of homogeneous glycans; however, enzyme-based routes typically require lengthy processes. Now, the design of a water-soluble affinity tag has enabled the automation of multistep enzymatic syntheses of mammalian oligosaccharides.
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Pohl, N.L.B. Robots command enzymes. Nature Chem 11, 201–203 (2019). https://doi.org/10.1038/s41557-019-0228-7
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DOI: https://doi.org/10.1038/s41557-019-0228-7
