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BACTERIAL PATHOGENESIS

Staphylococcus aureus blocks insulin function

The bacterial pathogen Staphylococcus aureus secretes a high-affinity insulin-binding protein that mediates insulin resistance, a major driver of obesity and type 2 diabetes, in a mouse model of infection.

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Fig. 1: eLtaS antagonizes insulin function.

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Correspondence to Christopher Weidenmaier.

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Weidenmaier, C. Staphylococcus aureus blocks insulin function. Nat Microbiol 3, 533–534 (2018). https://doi.org/10.1038/s41564-018-0153-3

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