Nonalcoholic fatty liver disease (NAFLD) has been thought to be associated with cardiovascular outcomes. A matched cohort study, including >18 million European adults, investigated the risk of acute myocardial infarction (AMI) or stroke in adults with NAFLD or nonalcoholic steatohepatitis (NASH). A diagnosis of NAFLD in routine care does not seem to be associated with risk of AMI or stroke after adjustment for established cardiovascular risk factors. The authors conclude that risk of cardiovascular disease should be assessed in the standard way in these patients, and that NAFLD should not be considered as a risk enhancer.
References
Original article
Alexander, M. et al. Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults. BMJ 367, I5367 (2019)
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Leake, I. NAFLD and risk of cardiovascular disease. Nat Rev Gastroenterol Hepatol 16, 706 (2019). https://doi.org/10.1038/s41575-019-0234-7
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41575-019-0234-7
This article is cited by
-
Association Between Blood Calcium, Magnesium, and Non-alcoholic Fatty Liver Disease in Adults: a Cohort-Based Case-Control Study
Biological Trace Element Research (2023)
