Extended Data Fig. 3: Fascia EPFs maintain position in steady conditions and recede from wounds over time. | Nature

Extended Data Fig. 3: Fascia EPFs maintain position in steady conditions and recede from wounds over time.

From: Patch repair of deep wounds by mobilized fascia

Extended Data Fig. 3

a, Dermal versus fascia EPFs chimeras in uninjured conditions. b, Fascia (left) or dermal (right) EPFs-traced chimeras. Representative images of 3 biological replicates. c, Scars at 70 dpw from deep injuries of fascia EPF-traced chimeras immunolabelled for DPP4. Representative images of 3 biological replicates. d, Cleaved CASP3 expression in wounds from fascia (left) or dermal (right) EPF-traced chimeras from deep (top) or superficial (bottom) injuries at 14 dpw. e, Fractions of fascia or dermal EPFs in the wound, dermis or fascia control regions positive for cleaved CASP3. Data are mean ± s.e.m.; n = 6 and 5 (fascia and dermal EPF, respectively) images analysed from 5 biological replicates. Lines delimit the border between fascia and dermis. Dotted lines delimit the wound or scar. Scale bars, 200 μm.

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