Extended Data Fig. 10: Quality of cryo-EM densities.
From: Structural basis of human transcription–DNA repair coupling
Cryo-EM density of the pulling hook (a), pulling hook wedging into the upstream fork of the transcription bubble (b), CSA-interacting motif (CIM) in CSB (c), ADP:BeF3 (d), beta-propellers in CSA-DDB1 (e–h), CSA-UVSSA (i) together with crosslinks used to position the VHS-domain of UVSSA (j), SPT6 and a zoom-in on the SPT6-Pol II stalk contacts (k), CTR9 and WDR61 (l), LEO1 C-terminal helix (m), CRL4CSA conformation targeting Pol II (n), CRL4CSA conformation targeting CSB (o). For each density we indicated from which structure the density was taken, Structure 1, 2, 3, 4 or 5.
