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Protein engineering

Hallucinating functional protein sequences

Nature Biotechnology volume 41, pages 1073–1074 (2023)Cite this article

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Functional proteins with limited homology to natural proteins are designed using a large language model.

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Fig. 1: ProGen.

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Author information

Authors and Affiliations

  1. Google Research, Mountain View, CA, USA

    David Belanger & Lucy J. Colwell

  2. Department of Chemistry, Cambridge University, Cambridge, UK

    Lucy J. Colwell

Authors
  1. David Belanger
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  2. Lucy J. Colwell
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Correspondence to Lucy J. Colwell.

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Competing interests

D.B. and L.J.C. have performed research as part of their employment at Google LLC. Google is a technology company that sells machine learning services as part of its business.

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Belanger, D., Colwell, L.J. Hallucinating functional protein sequences. Nat Biotechnol 41, 1073–1074 (2023). https://doi.org/10.1038/s41587-022-01634-2

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