Casey Weaver recounts how his group’s discovery of the TH17 pathway resolved several conundrums that had arisen in the wake of the original TH1–TH2 hypothesis.
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The author thanks others in his group as well as colleagues who have contributed much to the discoveries recounted in this article.
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Weaver, C.T. One road to the TH17 pathway: how TH1 led to TH17 (and vice versa), and first came last. Nat Immunol 21, 819–821 (2020). https://doi.org/10.1038/s41590-020-0715-4
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DOI: https://doi.org/10.1038/s41590-020-0715-4
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