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GENE REGULATION

Parsing the transcription factors governing T cell immunity

Zhong et al. exploit allelic variations in mice to pinpoint the ‘heavy lifter’ transcription factor families governing the chromatin landscape of resting and activated T cells.

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Fig. 1: Identifying the heavy lifter transcription factors that regulate the chromatin and transcriptional landscape during T cell activation.

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Correspondence to Rhys S. Allan.

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Johanson, T.M., Allan, R.S. Parsing the transcription factors governing T cell immunity. Nat Immunol 23, 3–4 (2022). https://doi.org/10.1038/s41590-021-01075-0

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