Extended Data Fig. 1: Human APOE variants modulate metastatic progression of murine melanoma.
From: Common germline variants of the human APOE gene modulate melanoma progression and survival
a, Relative expression of murine Apoe determined by qRT-PCR in B16F10 cells expressing shCtrl and shApoe hairpins and in YUMM1.7 cells (n = 3 cell culture replicates per group, graph represents mean values ± s.e.m.). b, Bioluminescence imaging of metastatic progression of murine melanoma B16F10-TR-shApoe cells intravenously injected into APOE knock-in mice (n = 10 mice per group; one-tailed Mann-Whitney test; graph represents mean values ± s.e.m.; representative of two independent experiments). Images correspond to representative mice on day 24 after injection.
