Extended Data Figure 6: Histology of OA/MF at 2 weeks and 8 weeks.
From: Articular cartilage regeneration by activated skeletal stem cells
a, Representative pentachrome stains and respective IF of (from left-right) ACAN, COL 1, COL 2, COL 10 and MMP 13 in 3 treatment conditions (top: PBS; middle: BMP2; bottom: BMP2 + sVEGFR1) at 2 weeks after MF. Scale bars 500μm. (n = 4 per group). b, Representative pentachrome stains and respective IF stains for the indicated markers in 3 treatment conditions (top row: PBS; middle: BMP2; bottom: BMP2 + sVEGFR1) at 8 weeks after MF. Scale bars 500μm. (n = 4 per group). c, Quantification of IF stains for the indicated markers at 2 weeks (top) and 8 weeks (bottom) after MF. (n = 3 per group per timepoint). Graphs show mean + /- s.e.m. Ordinary one-way ANOVA test with post-hoc analysis using Šídák method to compare between specific means. Exact P values to 2 significant figures.
