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NEUROLOGY

Treating cancer therapy–related cognitive impairment

Metformin can promote the regeneration of neural precursor cell populations and improve cognitive function in a preclinical model of cranial radiation and a pilot clinical study of children after cranial radiation and chemotherapy.

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Fig. 1: Use of metformin to treat NPC dysfunction after cancer therapy.

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Correspondence to Michelle Monje.

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Gibson, E.M., Monje, M. Treating cancer therapy–related cognitive impairment. Nat Med 26, 1174–1175 (2020). https://doi.org/10.1038/s41591-020-1014-1

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