Table 1 Body weight and organ mass in offspring of lean and obese mothers that consumed chow or HFD post-weaning

Final BW (g)

18.1 ± 0.2

20.9 ± 0.1^***

19.5 ± 0.3

28.04 ± 1.2^{†††/***}

F(1,52) = 62.33,P < 0.001

F(1,52) = 110.37, P < 0.001

F(1,52) = 27.24, P < 0.001

Liver (mg)

765 ± 14

693 ± 13^*

779 ± 43

852 ± 27^†††

F(1,48) = 11.9, P < 0.001

ns

F(1,48) = 8.4, P < 0.01

Muscle (mg)

Quad

236 ± 10

256 ± 11

247 ± 10

295 ± 8

F(1,50) = 5.7, P < 0.05

ns

AT

82 ± 4

88 ± 3

87 ± 3

98 ± 5

F(1,52) = 4.2, P < 0.05

F(1,52) = 4.9, p < 0.05

ns

Soleus

12.4 ± 0.7

15.9 ± 0.7

15.1 ± 0.7

19.6 ± 0.6

F(1,51) = 21.6, P < 0.001

F(1,51) = 34.7, p < 0.001

ns

WAT (mg)

Gonadal

141 ± 8

601 ± 89^***

231 ± 22

1348 ± 164^{†††/***}

F(1,51) = 22.3, P < 0.001

F(1,51) = 79.1, P < 0.001

F(1,51) = 13.7, P < 0.001

Inguinal

165 ± 11

463 ± 57^***

207 ± 13

823 ± 108^{†††/***}

F(1,49) = 12.4, P < 0.001

F(1,49) = 63.7, P < 0.001

F(1,49) = 7.7, P < 0.01

RP

26.1 ± 2.3

143.0 ± 25.2^***

44.5 ± 4.2

347.5 ± 33.5^{†††/***}

F(1,52) = 29.9, P < 0.001

F(1,52) = 106.5, P < 0.001

F(1,52) = 20.9, P < 0.001

Plasma Insulin (ng/mL)

0.085 ± 0.020

0.154 ± 0.016^***

0.166 ± 0.020

0.420 ± 0.0.038^{†††/***}

F(1,32) = 38.2, P < 0.001

F(1,32) = 33.2, P < 0.001

F(1,32) = 10.9, P < 0.01

2.82 ± 0.24

3.21 ± 0.16^**

2.94 ± 0.11

3.62 ± 0.22^**

ns

F(1,36) = 7.8, P < 0.01

ns