Table 1 Statistically significant differentially expressed mRNAs and lncRNAS number in PBMC from ALS patients, in terms of up-regulated transcripts, down-regulated transcripts and total. Counts are reported for sporadic ALS patients (SALS) and for mutated patients (FUS, TARDPB and SOD1).

From: Long non-coding and coding RNAs characterization in Peripheral Blood Mononuclear Cells and Spinal Cord from Amyotrophic Lateral Sclerosis patients

 

SALS

FUS

TARDB

SOD1

mRNAs

lncRNAs

mRNAs

lncRNAs

mRNAs

lncRNAs

mRNAs

lncRNAs

UP-regulated

57

183

35

16

10

6

14

0

DOWN-regulated

30

110

87

5

20

9

4

2

total

87

293

122

21

30

15

18

2

  1. Transcripts were considered as differentially expressed when |log2(disease sample/healthy control)| ≥ 1 and a FDR ≤ 0.1.
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