Table 4 Hazard ratios (95% confidence intervals) for new-onset diabetes according to changes in BMI.

From: Impact of weight changes on the incidence of diabetes mellitus: a Korean nationwide cohort study

Group

BMI changes

2002 → 2006 Incidence ratea

HR (95% CI)

2002 → 2004 Incidence ratea

HR (95% CI)

Unadjusted

Age-, sex-adjusted

MVb-adjusted

Unadjusted

Age-, sex-adjusted

MVb-adjusted

Non-OB

>−9%

2.3

0.43 (0.30–0.60)

0.52 (0.37–0.74)

0.51 (0.35–0.74)

3.4

0.60 (0.41–0.87)

0.68 (0.47–0.99)

0.73 (0.50–1.07)

−9–−6%

3.2

0.59 (0.46–0.77)

0.68 (0.52–0.88)

0.66 (0.50–0.88)

3.0

0.53 (0.39–0.72)

0.58 (0.43–0.79)

0.61 (0.44–0.84)

−6 – −3%

3.9

0.71 (0.60–0.85)

0.80 (0.67–0.96)

0.81 (0.67–0.98)

4.8

0.85 (0.72–1.00)

0.94 (0.80–1.10)

0.89 (0.75–1.07)

−3–3%

5.5

1

1

1

5.6

1

1

1

3–6%

7.2

1.31 (1.13–1.52)

1.16 (1.00–1.34)

1.17 (0.99–1.36)

5

0.89 (0.76–1.05)

0.80 (0.68–0.95)

0.78 (0.65–0.92)

6–9%

8.1

1.46 (1.20–1.78)

1.26 (1.03–1.53)

1.20 (0.97–1.48)

7.5

1.34 (1.07–1.66)

1.19 (0.95–1.48)

1.13 (0.90–1.43)

>9%

6.4

1.16 (0.89–1.51)

0.93 (0.71–1.22)

0.92 (0.70–1.23)

7.3

1.30 (0.97–1.76)

1.08 (0.80–1.45)

1.04 (0.75–1.43)

P

 

<0.001

<0.001

<0.001

3.4

<0.001

<0.001

0.002

OB

>−9%

8.9

0.61 (0.48–0.76)

0.73 (0.59–0.92)

0.74 (0.59–0.95)

9.9

0.72 (0.53–0.99)

0.84 (0.61–1.15)

0.77 (0.54–1.09)

−9–−6%

10.7

0.73 (0.60–0.89)

0.81 (0.67–0.99)

0.83 (0.68–1.03)

11.0

0.80 (0.63–1.01)

0.91 (0.72–1.15)

0.89 (0.69–1.14)

−6–−3%

12.2

0.83 (0.72–0.96)

0.88 (0.76–1.01)

0.89 (0.77–1.04)

13.8

1.01 (0.87–1.16)

1.06 (0.92–1.23)

1.01 (0.86–1.19)

−3–3%

14.6

1

1

1

13.7

1

1

1

3–6%

15.5

1.06 (0.89–1.26)

1.02 (0.86–1.21)

1.05 (0.87–1.26)

13.5

0.98 (0.83–1.16)

0.95 (0.80–1.12)

0.93 (0.78–1.11)

6–9%

18.7

1.28 (0.99–1.65)

1.25 (0.97–1.61)

1.32 (1.01–1.73)

12.4

0.90 (0.68–1.19)

0.88 (0.66–1.16)

0.81 (0.60–1.11)

>9%

13.5

0.92 (0.61–1.40)

0.93 (0.61–1.40)

0.74 (0.45–1.19)

18.1

1.32 (0.96–1.80)

1.30 (0.95–1.78)

1.35 (0.98–1.87)

P

 

<0.001

<0.001

<0.001

 

0.074

0.328

0.466

  1. aPer 1000 person-years. bMV includes age, sex, current smoking, alcohol drinking, exercise, income, hypertension, dyslipidemia, and a family history of diabetes.