Table 4 Hazard ratios (95% confidence intervals) for new-onset diabetes according to changes in BMI.
From: Impact of weight changes on the incidence of diabetes mellitus: a Korean nationwide cohort study
Group | BMI changes | 2002 → 2006 Incidence ratea | HR (95% CI) | 2002 → 2004 Incidence ratea | HR (95% CI) | ||||
---|---|---|---|---|---|---|---|---|---|
Unadjusted | Age-, sex-adjusted | MVb-adjusted | Unadjusted | Age-, sex-adjusted | MVb-adjusted | ||||
Non-OB | >−9% | 2.3 | 0.43 (0.30–0.60) | 0.52 (0.37–0.74) | 0.51 (0.35–0.74) | 3.4 | 0.60 (0.41–0.87) | 0.68 (0.47–0.99) | 0.73 (0.50–1.07) |
−9–−6% | 3.2 | 0.59 (0.46–0.77) | 0.68 (0.52–0.88) | 0.66 (0.50–0.88) | 3.0 | 0.53 (0.39–0.72) | 0.58 (0.43–0.79) | 0.61 (0.44–0.84) | |
−6 – −3% | 3.9 | 0.71 (0.60–0.85) | 0.80 (0.67–0.96) | 0.81 (0.67–0.98) | 4.8 | 0.85 (0.72–1.00) | 0.94 (0.80–1.10) | 0.89 (0.75–1.07) | |
−3–3% | 5.5 | 1 | 1 | 1 | 5.6 | 1 | 1 | 1 | |
3–6% | 7.2 | 1.31 (1.13–1.52) | 1.16 (1.00–1.34) | 1.17 (0.99–1.36) | 5 | 0.89 (0.76–1.05) | 0.80 (0.68–0.95) | 0.78 (0.65–0.92) | |
6–9% | 8.1 | 1.46 (1.20–1.78) | 1.26 (1.03–1.53) | 1.20 (0.97–1.48) | 7.5 | 1.34 (1.07–1.66) | 1.19 (0.95–1.48) | 1.13 (0.90–1.43) | |
>9% | 6.4 | 1.16 (0.89–1.51) | 0.93 (0.71–1.22) | 0.92 (0.70–1.23) | 7.3 | 1.30 (0.97–1.76) | 1.08 (0.80–1.45) | 1.04 (0.75–1.43) | |
P | <0.001 | <0.001 | <0.001 | 3.4 | <0.001 | <0.001 | 0.002 | ||
OB | >−9% | 8.9 | 0.61 (0.48–0.76) | 0.73 (0.59–0.92) | 0.74 (0.59–0.95) | 9.9 | 0.72 (0.53–0.99) | 0.84 (0.61–1.15) | 0.77 (0.54–1.09) |
−9–−6% | 10.7 | 0.73 (0.60–0.89) | 0.81 (0.67–0.99) | 0.83 (0.68–1.03) | 11.0 | 0.80 (0.63–1.01) | 0.91 (0.72–1.15) | 0.89 (0.69–1.14) | |
−6–−3% | 12.2 | 0.83 (0.72–0.96) | 0.88 (0.76–1.01) | 0.89 (0.77–1.04) | 13.8 | 1.01 (0.87–1.16) | 1.06 (0.92–1.23) | 1.01 (0.86–1.19) | |
−3–3% | 14.6 | 1 | 1 | 1 | 13.7 | 1 | 1 | 1 | |
3–6% | 15.5 | 1.06 (0.89–1.26) | 1.02 (0.86–1.21) | 1.05 (0.87–1.26) | 13.5 | 0.98 (0.83–1.16) | 0.95 (0.80–1.12) | 0.93 (0.78–1.11) | |
6–9% | 18.7 | 1.28 (0.99–1.65) | 1.25 (0.97–1.61) | 1.32 (1.01–1.73) | 12.4 | 0.90 (0.68–1.19) | 0.88 (0.66–1.16) | 0.81 (0.60–1.11) | |
>9% | 13.5 | 0.92 (0.61–1.40) | 0.93 (0.61–1.40) | 0.74 (0.45–1.19) | 18.1 | 1.32 (0.96–1.80) | 1.30 (0.95–1.78) | 1.35 (0.98–1.87) | |
P | <0.001 | <0.001 | <0.001 | 0.074 | 0.328 | 0.466 |