Table 1 Clinical characteristics of PE and control groups.

From: Early Detection of Preeclampsia Using Circulating Small non-coding RNA

Characteristic

Control (n = 40)

PE (n = 35)

p-value

Maternal age, years (IQR)

31.3 (25.9–34.6)

29.9 (28.1–34.5)

0.9200

Body Mass Index, kg/m2 (IQR)

24.1 (22.6–28.7)

28.4 (24.4–31.7)

0.0125

Gestational age, weeks (IQR)

12.8 (12.3–13.2)

12.7 (12.2–13.1)

0.3916

Crown-rump length, mm (IQR)

63.9 (57.5–70.2)

62.9 (56.2–67.9)

0.3029

Mean arterial pressure (MAP), mm Hg (IQR)

83.2 (79.4–87.7)

97.1 (90.1–108.7)

<0.0001

Uterine artery pulsatility index (UT PI) (IQR)

1.5 (1.3–1.7)

2.5 (2–2.8)

<0.0001

Gestational age at delivery, weeks (IQR)

39.8 (39.4–40.7)

31.4 (29.4–33.2)

<0.0001

Birth weight, g (IQR)

3,420 (3,198–3,578)

1,222 (951–1,565)

<0.0001

Fetal Gender, n(%)

  

0.65

   female

22 (55)

17 (42.5)

 

   male

18 (45)

18 (45)

 

Ethnicity, n(%)

  

0.2848

   Afro-Caribbean

15 (37.5)

19 (54.3)

 

   South Asian

1 (2.5)

1 (2.9)

 

   Caucasian

24 (60)

15 (42.9)

 

Cigarette smokers, n(%)

  

0.11

   No smoker

34 (85)

34 (97.1)

 

   Smoker

6 (15)

1 (2.9)

 

Family history of preeclampsia, n(%)

  

0.41

   Yes

2 (5)

4 (11.4)

 

   No

38 (95)

31 (88.6)

 

Parity, n(%)

  

0.0018

   Multiparous with no previous PE

15 (37.5)

6 (17.1)

 

   Multiparous with previous PE

0 (0)

8 (22.9)

 

   Nulliparous

25 (62.5)

21 (60)

 

Chronic hypertension, n(%)

  

0.001

   Yes

0 (0)

8 (22.9)

 

   No

40 (100)

27 (77.1)

 
  1. A comparison of maternal and pregnancy characteristics between the two groups: pregnant women that have developed preeclampsia (PE) and pregnant women with uncomplicated pregnancies (control). P-values were calculated using Fisher exact test for categorical variables, and using Mann-Whitney U test for continuous variables.