Table 6 List of downregulated genes of UA159 in the presence of S-PRG eluate, which were observed in either MT8148 or UA159 under three different conditions using DNA microarray analysis.

From: Inhibitory effect of surface pre-reacted glass-ionomer (S-PRG) eluate against adhesion and colonization by Streptococcus mutans

Gene	Accession number	S-PRG 0%	S-PRG 6.3%			S-PRG12.5%			S-PRG 25.0%
Gene	Accession number	Signal	Signal	Log2*	Change^#	Signal	Log2*	Change^#	Signal	Log2*	Change^#
bcc	721410.1	5980.6	1943.9	−1.62	0.325	1876.8	−1.67	0.314	1108.3	−2.43	0.185
celR	721935.1	11936	1137.1	−3.4	0.095	366.9	−5.02	0.031	38.4	−8.3	0.003
cilA	721415.1	5421.4	1804.4	−1.59	0.332	1879	−1.53	0.347	726.1	−2.9	0.134
cilB	721414.1	3708.8	1459.6	−1.34	0.394	1488.8	−1.32	0.402	712.4	−2.38	0.192
cilG	721413.1	4245.9	1734	−1.29	0.408	1999.6	−1.09	0.471	1059.9	−2	0.249
citC	721405.1	1927.9	218.7	−3.15	0.113	121.6	−3.99	0.063	164.4	−3.55	0.085
citG	721406.1	1543.6	282.1	−2.45	0.183	138.2	−3.48	0.089	183.1	−3.1	0.117
citG2	721416.1	5644.4	1906.9	−1.56	0.338	1774.5	−1.67	0.314	694.5	−3.02	0.123
coaA	721513.1	126.2	39.1	−1.69	0.31	49.8	−1.34	0.395	54.6	−1.21	0.433
comEA	721053.1	135.8	67.9	−1	0.5	29.2	−2.22	0.215	29.5	−2.21	0.217
comYA	722285.1	231.2	37.6	−2.65	0.159	17.9	−3.74	0.075	28.8	−3.02	0.124
comYB	722284.1	606.2	90	−2.76	0.148	42	−3.87	0.069	69	−3.14	0.113
comYC	722283.1	903.7	109.7	−3.05	0.121	45.5	−4.34	0.049	102.2	−3.14	0.113
comYD	722282.1	750.9	89.6	−3.13	0.114	38	−4.34	0.05	70.7	−3.43	0.093
galR	721293.1	998.6	467	−1.1	0.468	222.2	−2.17	0.222	396.7	−1.33	0.397
grpE	720560.1	40392.6	24381	−0.72	0.603	15498.9	−1.38	0.384	23261.7	−0.8	0.576
hsdM	721299.1	236.4	230.2	−0.04	0.974	233.2	−0.02	0.986	693.4	1.55	2.933
lacA	721844.1	1232.9	487.2	−1.34	0.395	115.2	−3.42	0.093	34	−5.19	0.027
lacB	721843.1	3958.7	974.1	−2.02	0.246	263.3	−3.91	0.066	59.5	−6.09	0.015
lacC	721842.1	2894.5	707.6	−2.03	0.245	203.3	−3.83	0.07	44.2	−6.07	0.015
lacD	721841.1	2529.6	976.9	−1.37	0.386	173.4	−3.88	0.068	25.2	−6.65	0.01
lacD2	720591.1	1990.2	422.6	−2.24	0.212	162.4	−3.61	0.082	39.2	−5.67	0.02
lacE	721839.1	4352.6	1160.3	−1.91	0.267	303.3	−3.85	0.07	71.2	−5.93	0.016
lacF	721840.1	3438.8	936	−1.88	0.272	227.8	−3.92	0.066	38.3	−6.54	0.011
lacG	721838.1	30256.7	6224.5	−2.28	0.206	1223.1	−4.63	0.04	270.5	−6.81	0.009
lacX	721837.1	2139.1	804.4	−1.41	0.376	251.6	−3.09	0.118	84.2	−4.67	0.039
lytR	721011.1	1717.4	772.8	−1.15	0.45	841.5	−1.03	0.49	419.1	−2.04	0.244
oadB	721411.1	11315.4	4350.1	−1.38	0.384	4811.2	−1.23	0.425	2660.8	−2.09	0.235
pflC	720930.1	1164.2	478.1	−1.28	0.411	391.9	−1.57	0.337	544.7	−1.1	0.468
ptcA	721934.1	7508.6	633.3	−3.57	0.084	207.5	−5.19	0.027	17.7	−8.74	0.002
ptcB	721936.1	615.6	239.6	−1.37	0.388	103.5	−2.58	0.167	21.7	−4.84	0.035
ptcC	721932.1	2921	366.2	−3	0.125	124.6	−4.56	0.043	38.5	−6.25	0.013
pycB	721417.1	22423.4	5598.4	−2	0.25	4989.7	−2.17	0.223	2210.2	−3.34	0.099
rgpG	720710.1	1621.9	1575.5	−0.04	0.971	1983.1	0.29	1.223	4685.6	1.53	2.889
scnE	722129.1	324.3	412.9	0.35	1.273	291.9	−0.15	0.9	284	−0.19	0.876
spaP	721042.1	3168.9	3842.9	0.28	1.212	2127.1	−0.58	0.671	2296.4	−0.47	0.724
ssb2	722266.1	769.7	369.5	−1.06	0.48	271.3	−1.51	0.352	308.6	−1.32	0.401
trk	721902.1	14957.3	11522.8	−0.38	0.77	10018.8	−0.58	0.67	3609	−2.05	0.241
trkB	721901.1	10436.8	7856.4	−0.41	0.753	7320	−0.51	0.701	2494.6	−2.06	0.239
wapA	721382.1	3891.4	2323.7	−0.74	0.597	1931.4	−1.01	0.496	568.7	−2.78	0.146

^*Log2 means Log2 ratio. ^#Change means Fold change. The Log2 ratio and Fold change were calculated by signal with each concentration of S-PRG eluate/signal without S-PRG eluate.

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Table 6 List of downregulated genes of UA159 in the presence of S-PRG eluate, which were observed in either MT8148 or UA159 under three different conditions using DNA microarray analysis.

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