Figure 2 | Scientific Reports

Figure 2

From: Aloperine Protects Mice against Bleomycin-induced Pulmonary Fibrosis by Attenuating Fibroblast Proliferation and Differentiation

Figure 2

Administration of aloperine attenuated lung fibrosis after BLM induction. (A) Analysis of fibrotic markers in lung homogenates. Left panel: representative western blot results for fibronectin, collagen I, and α-SMA expression. Right panel: graphic figures showing the western blot results of all mice examined. (B–D) RT-PCR analysis of fibronectin, collagen I, and α-SMA expression in the lung induced by BLM. (E) The rates of hydroxyproline and lung wet weight of all mice studied. Six to 7 mice were included in each study group. Statistical analysis was performed by one-way ANOVA with Newman-Keuls post-hoc test. *p < 0.05; **p < 0.01; ***p < 0.001.

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