Figure 7
Investigation of neuronal stability markers. Western blot analysis of isolated prefrontal cortex tissues revealed changes in neuronal stability markers: synapsin 1 (A) and PSD95 (B). (A) A significant increase in synapsin 1 levels were observed in the 50 cGy + PLX group when compared to 50 cGy alone. Representative blot depicted below. (B) A significant decrease in PSD-95 levels were observed in the 50 cGy + PLX group when compared to 50 cGy alone. Representative blot depicted below. Full-length blots are presented in Supplemental Fig. 2. Samples were derived from the same experiment and were processed in parallel. Unpaired student t-tests reveal significant differences between groups. *p < 0.05, **p < 0.01. Individual animal scores represented in dots, bars depict group mean and SEM. N = 7–8 each group.
