Table 2 CFT073 induced gene downregulation compared to unstimulated renal fibroblasts.
Gene symble | Fold change | Description |
|---|---|---|
KIT | −24,3 | Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
PTCH1 | −13,1 | Homo sapiens patched 1 |
TET1 | −9,3 | Homo sapiens tet methylcytosine dioxygenase 1 |
CEBPA-AS1 | −8,6 | Homo sapiens CEBPA antisense RNA 1 |
PLCB2 | −8,2 | Homo sapiens phospholipase C, beta 2 |
EEPD1 | −7,7 | Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1 |
CPEB1 | −7,6 | Homo sapiens cytoplasmic polyadenylation element binding protein 1 |
FIGNL2 | −7,0 | Homo sapiens fidgetin-like 2 |
GRASP | −6,9 | Homo sapiens GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein |
TOX | −6,7 | Homo sapiens thymocyte selection-associated high mobility group box |
MKNK2 | −6,6 | Homo sapiens MAP kinase interacting serine/threonine kinase 2 |
STAM-AS1 | −6,6 | Homo sapiens STAM antisense RNA 1 |
SNHG22 | −6,6 | Homo sapiens small nucleolar RNA host gene 22 |
ADRA2A | −6,3 | Homo sapiens adrenoceptor alpha 2A |
RCOR2 | −6,2 | Homo sapiens REST corepressor 2 |
CEBPA | −6,1 | Homo sapiens CCAAT/enhancer binding protein (C/EBP), alpha |
SSTR1 | −5,9 | Homo sapiens somatostatin receptor 1 |
CSRNP3 | −5,8 | Homo sapiens cysteine-serine-rich nuclear protein 3 |
RGCC | −5,8 | Homo sapiens regulator of cell cycle |
MEX3B | −5,7 | Homo sapiens mex-3 RNA binding family member B |
THBD | −5,7 | Homo sapiens thrombomodulin |
ZNF518A | −5,6 | zinc finger protein 518A |
EPHB3 | −5,6 | Homo sapiens EPH receptor B3 |
GAS6-AS1 | −5,6 | Homo sapiens cDNA FLJ35543 fis, clone SPLEN2002957 |
E2F7 | −5,5 | Homo sapiens E2F transcription factor 7 |
KCNE3 | −5,5 | Homo sapiens potassium channel, voltage gated subfamily E regulatory beta subunit 3 |
CAMKK1 | −5,5 | Homo sapiens calcium/calmodulin-dependent protein kinase kinase 1, alpha |
GAS1 | −5,3 | Homo sapiens growth arrest-specific 1 |
TRIM45 | −5,3 | Homo sapiens tripartite motif containing 45 |
SLC52A1 | −5,3 | Homo sapiens solute carrier family 52 |
