Table 3 Hazard Ratio for the Association between Rotavirus Vaccination and Type 1 Diabetes, 2006–2017.
Unadjusted Hazard Ratio | 95% CI | p value | Adjusted Hazard Ratio | 95% CI | p value | |
---|---|---|---|---|---|---|
Vaccination | ||||||
Completed Rotavirus Series | 0.64 | 0.52, 0.79 | <0.001 | 0.67 | 0.54, 0.83 | <0.001 |
Not vaccinated | 1.00 | (reference) | ||||
Sex | ||||||
Girls | 1.04 | 0.84, 1.28 | 0.734 | |||
Boys | 1.00 | (reference) | ||||
Season of Birth | ||||||
Spring | 1.55 | 1.12, 2.14 | 0.008 | |||
Summer | 1.36 | 0.98, 1.90 | 0.068 | |||
Autumn | 1.42 | 1.02, 1.97 | 0.039 | |||
Winter | 1.00 | (reference) | ||||
Residence at Birth | ||||||
New England, New Jersey | 1.00 | (reference) | ||||
New York, Pennsylvania | 0.84 | 0.49, 1.44 | 0.533 | |||
Middle Atlantic | 0.78 | 0.49, 1.26 | 0.315 | |||
Southeast | 0.64 | 0.41, 1.00 | 0.051 | |||
Michigan, Indiana, Ohio, Kentucky | 0.81 | 0.50, 1.32 | 0.399 | |||
North Central | 0.55 | 0.33, 0.92 | 0.023 | |||
Middle Central | 0.58 | 0.34, 0.99 | 0.047 | |||
South Central | 0.51 | 0.32, 0.82 | 0.005 | |||
Mountain | 0.90 | 0.57, 1.42 | 0.640 | |||
Pacific | 0.87 | 0.56, 1.35 | 0.542 |