Table 3 Hazard Ratio for the Association between Rotavirus Vaccination and Type 1 Diabetes, 2006–2017.

From: Lower Incidence Rate of Type 1 Diabetes after Receipt of the Rotavirus Vaccine in the United States, 2001–2017

 

Unadjusted Hazard Ratio

95% CI

p value

Adjusted Hazard Ratio

95% CI

p value

Vaccination

   Completed Rotavirus Series

0.64

0.52, 0.79

<0.001

0.67

0.54, 0.83

<0.001

   Not vaccinated

   

1.00

(reference)

 

Sex

   Girls

   

1.04

0.84, 1.28

0.734

   Boys

   

1.00

(reference)

 

Season of Birth

   Spring

   

1.55

1.12, 2.14

0.008

   Summer

   

1.36

0.98, 1.90

0.068

   Autumn

   

1.42

1.02, 1.97

0.039

   Winter

   

1.00

(reference)

 

Residence at Birth

   New England, New Jersey

   

1.00

(reference)

 

   New York, Pennsylvania

   

0.84

0.49, 1.44

0.533

   Middle Atlantic

   

0.78

0.49, 1.26

0.315

   Southeast

   

0.64

0.41, 1.00

0.051

   Michigan, Indiana, Ohio, Kentucky

   

0.81

0.50, 1.32

0.399

   North Central

   

0.55

0.33, 0.92

0.023

   Middle Central

   

0.58

0.34, 0.99

0.047

   South Central

   

0.51

0.32, 0.82

0.005

   Mountain

   

0.90

0.57, 1.42

0.640

   Pacific

   

0.87

0.56, 1.35

0.542