Figure 3 | Scientific Reports

Figure 3

From: The interaction of Multiple Sclerosis risk loci with Epstein-Barr virus phenotypes implicates the virus in pathogenesis

Figure 3

(A) MS risk SNP genotype effects on each trait; DNA-QTL (genotype effect on EBV DNA copy number), EBV mir-QTL (genotype effect on EBV miRNA expression level), IG-QTL (genotype effect on LCL intrinsic growth rate) and LCLeQTL (genotype effect on host genes within a 1 mega base window from the SNP). (B) The overlap between the MS risk SNPs which are DNA-QTLs, EBV mir-QTLs and LCLeQTLs. (C) The rs7260482 SNP as is associated with EBV DNA copy number, EBV miRNA expression (BART4-3p and BART3-5p) and expression level of the proximal MS risk gene (PVR).

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