Figure 3 | Scientific Reports

Figure 3

From: Pharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization

Figure 3

Breed differences in CYP2B11 protein and mRNA. Microsomal CYP2B11 protein content (a) and CYP2B11 mRNA abundance (b) were measured in the same set of livers obtained from Beagles (n = 5), mixed-breed dogs (n = 5) and Greyhounds (n = 5). Data are expressed relative to the liver with the lowest value. Shown are box and whiskers plots summarizing data for individual dogs in each breed group. Significant differences between breed groups were identified by ANOVA on log transformed data (P < 0.05) for both CYP2B11 protein and mRNA. Shown for each set of data are the P-values for post hoc pairwise multiple comparisons testing (Holm-Sidak method).

Back to article page