Table 5 Comparison of the LoS scores, obtained observationally and through determining the surface area projection of the targeted OMC on the nostril plane.
From: Numerical evaluation of spray position for improved nasal drug delivery
Observational LoS score | Nostril SA (mm2) | OMC SA Projection (mm2) | OMC SA projection as % of Nostril SA | SA-based LoS score | Pearson’s correlation between two sets of scores | SA-based scoring criteria | ||
---|---|---|---|---|---|---|---|---|
NPM1 | 4 | 103.9367 | 6.9209 | 6.66% | 4 | 0.85 | >6% | 4 |
NPM2 | 3 | 83.3166 | 1.4370 | 1.72% | 2 | > 4% | 3 | |
NPM3 | 3 | 67.1599 | 5.0085 | 7.46% | 4 | >1.5% | 2 | |
NPM4 | 2 | 109.9467 | 2.5846 | 2.35% | 2 | >0% | 1 | |
NPM5 | 1 | 104.1179 | 0.0904 | 0.09% | 1 | SA = surface area |