Table 1 Clinicopathological characteristics of study patients.

From: Combination of lymphocyte count and albumin concentration as a new prognostic biomarker for rectal cancer

Variables

n = 240, median [range], n(%)

Age

66 [21–90]

Sex

Male

163 (68)

Female

77 (32)

Tumor location

Ra

122 (51)

Rb-P

118 (49)

cStage

II

73 (30)

III

167 (70)

CEA

16.4 ± 9.7

Preoperative treatment

none

170 (71)

nCRT

24 (10)

NAC

46 (19)

Surgical procedure

LAR

158 (66)

ISR

32 (13)

APR

39 (16)

TPE

4 (2)

Hartmann

7 (3)

Surgical approach

Laparoscopic

201 (84)

Robot

23 (10)

Open

10 (4)

Conversion

6 (2)

pT classification

pT1/T2

75 (31)

pT3/T4

165 (69)

pN classification

negative

157 (65)

positive

83 (35)

Histology

well/mod

223 (93)

por/muc

16 (7)

Adjuvant Chemotherapy

107 (45)

Inflammation parameters

Neutrophil (/µL)

3467 [768–13,275]

Lymphocyte (/µL)

1472 [67.2–28,079]

Platelet (/µL)

224,500 [16,000–523,000]

Monocyte (/µL)

341 [151–1344]

Albumin (g/dL)

4.0 [2.0–4.9]

CRP (mg/dL)

 0

57 (24)

 0 < , ≤ 0.2

124 (52)

 0.2 < , ≤ 1.0

45 (19)

 1.0 < 

14 (5)

Combinations

NLR

2.31 [0.15–64.4]

PLR

140 [10–286]

PAR

56,300 [4000–223,000]

LMR

4.53 [0.24–81.06]

MAR

85.2 [32.7–413.3]

NP

767,460 [20,748–5,408,480] (× 103)

LA

5950 [275.5–10,951]

NM

1,219,048 [227,697–13,069,600]

MP

76,682 [3057–322,560] (× 103)

GPS

0

224 (93)

1

6 (3)

2

10 (4)

SIS

0

66 (28)

1

115 (48)

2

59 (24)

  1. CEA carcinoembryonic antigen, nCRT neoadjuvant chemoradiotherapy, NAC neoadjuvant chemotherapy, LAR low anterior resection, ISR intersphincteric resection, APR abdominoperineal resection, TPE total pelvic exenteration, well/mod well-differentiated/moderately-differentiated, por/muc poorly-differentiated/mucinous, CRP C-reactive protein, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, PAR platelet-to-albumin ratio, LMR lymphocyte-to-monocyte ratio, MAR monocyte-to-albumin ratio, NP neutrophil × platelet, LA lymphocyte × albumin, NM neutrophil × monocyte, and MP monocyte × platelet, GPS Glasgow prognostic scale, SIS systemic inflammation scale.
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