Table 2 Extracellular free water, blood markers and cognitive data at baseline and follow-up visits.
From: A longitudinal analysis of brain extracellular free water in HIV infected individuals
Parameter | BSL | W12 | Y1 | Y2 | ||||
|---|---|---|---|---|---|---|---|---|
HIV+ | HIV− | HIV+ | HIV− | HIV+ | HIV− | HIV+ | HIV− | |
Participants (n) | 44 | 52 | 38 | 0 | 29 | 46 | 19 | 41 |
FW index (%) | ||||||||
GM | 17.42 ± 0.44 | 13.76 ± 0.64 | 14.41 ± 0.91 | – | 17.91 ± 0.48 | 17.72 ± 0.41 | 18.08 ± 0.59 | 18.03 ± 0.38 |
WM | 4.82 ± 0.12 | 4.46 ± 0.12 | 4.44 ± 0.15 | – | 4.87 ± 0.15 | 4.98 ± 0.11 | 4.86 ± 0.21 | 4.99 ± 0.11 |
Blood markers | ||||||||
CD4+ | 509.66 ± 41.24 | – | 587.00 ± 47.20 | – | 703.76 ± 58.14 | – | 787.78 ± 67.95 | – |
VL (× 102) | 782.36 ± 205.85 | – | 4.31 ± 3.96 | – | 12.39 ± 12.23 | – | 0.22 ± 0.08 | – |
NfL | 14.65 ± 3.37 | 7.32 ± 0.56* | 10.04 ± 1.67 | – | 10.37 ± 2.98 | – | 10.55 ± 2.62 | 7.51 ± 0.59+ |
Total cognitive score | − 1.62 ± 0.56 | 0.21 ± 0.59 | − 0.19 ± 0.63 | – | − 0.42 ± 0.71 | 1.64 ± 0.75 | − 0.46 ± 0.93 | 2.41 ± 0.78 |
