Figure 2
From: Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels
The fate of of PDGFRa+ cells during a long-term homeostasis of the aortic wall. (A) Schematic outlining the experimental strategy. (B) Representative images of the initial labeling at 2 months of age in different portions of large arteries. L: lumen, Asc Aorta: ascending aorta, Des Aorta: descending aorta. Scale bars: 100 µm. (C) Representative images of 2-year-chase in different portions of larger arteries. L: lumen, Asc Aorta: ascending aorta, Des Aorta: descending aorta. Scale bars: 100 µm. (D, E) Immunostaining for Sca1 (D) and SM-MHC (E) in the aortas at 2-year-chase. Arrows indicate tdTomato+ /Sca1+ adventitial cells. L: lumen, Asc Aorta: ascending aorta, Des Aorta: descending aorta. Scale bars: 100 µm. See also Figure S3.
