Table 3 Unadjusted independent variables of appendicitis in 51 children with appendicitis and 82 healthy controls.

From: Associations of hair cortisol concentrations with paediatric appendicitis

 

Appendicitis (n = 51)

Controls

(n = 82)

OR (95% CI)

p value

Age (years)

9 (1–13)

6 (1–15)

1.11 (1.02–1.22)

0.021

Sex (Male)

26 (51%)

38 (41%)

0.68 (0.34–1.37)

0.284

Viral infections < 6 m

2 (0–5)

2 (0–8)

0.94 (0.74–1.19)

0.600

Bacterial infections < 6 m

0 (0–2)

0 (0–1)

1.16 (0.30–4.48)

0.825

Surgery < 6 m

0 (0%)

2 (2%)

–

–

Serious illness < 6 m

5a (10%)

1b (1%)

8.8 (0.998–77.67)

0.050

Serious life events < 6 m

4c (8%)

0 (0%)

–

–

Season

   

0.021

Winter

8 (16%)

25 (30%)

0.58 (0.23–1.51)

0.264

Spring

9 (18%)

2 (2%)

8.18 (1.62–41.26)

0.011

Summer

12 (24%)

15 (18%)

1.45 (0.58–3.65)

0.425

Autumn

22 (43%)

40 (49%)

1

 

HCC 0–3 months (pg/mg)

21.3 (6.7–373.7)

24.1 (6.0–606.7)

0.89 (0.37–2.15)

0.80

HCC 4–6 months (pg/mg)

13.7 (4.1–1524.5)

25.1 (5.8–979.12)

0.46 (0.19–1.10)

0.081

Difference in HCC (%)

123 (16–441)

100 (15–182)

7.52 (2.49–22.67)

0.001

  1. Values presented as median (min–max) or as absolute number (percentage of patients).
  2. M: male, F: female. n = 106 (66 controls, 40 cases) for HCC 4–6 months and difference in HCC.
  3. a) 2 fractures, 1 thyrotoxicosis, 1 severe autism, 1 severe ADHD; b) urinary tract disorder with long-term catheter; c) 1 with severely depressed father, 2 with domestic abuse, 1 with loss of close relative.
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