Table 1 LTRS/LVDS vs NP trajectory differences and effect sizes (Cohen’s d).

From: Using a Digital Neuro Signature to measure longitudinal individual-level change in Alzheimer’s disease: the Altoida large cohort study

Healthy LTRS/LVDS vs NP

t Value

p Value

Cohen’s d

95% CI

 

MCI LTRS/LVDS vs NP

t Value

p Value

Cohen’s d

95% CI

 

AD LTRS/LVDS vs NP

t Value

p Value

Cohen’s d

95% CI

 

M0–M6

10.37

0.009

1.1893

0.9438

1.4349

M0–M6

4.06

0.056

0.5742

0.2913

0.857

M0–M6

7.33

0.018

1.639

1.1325

2.1456

M6–M12

12.48

0.006

1.4411

1.1871

1.6951

M6–M12

9.67

0.011

1.3675

1.0597

1.6754

M6–M12

7.92

0.016

1.771

1.2539

2.288

M12–M18

12.50

0.006

1.4434

1.1893

1.6975

M12–M18

26.92

0.001

3.8071

3.3423

4.2718

M12–M18

7.25

0.018

1.6211

1.116

2.1263

M18–M24

13.82

0.005

1.5958

1.3359

1.8556

M18–M24

11.52

0.007

1.6292

1.3093

1.949

M18–M24

36.20

0.001

8.0946

6.766

9.4232

M24–M30

28.17

0.001

3.2528

2.9079

3.5977

M24–M30

11.23

0.008

1.5882

1.2703

1.906

M24–M30

12.85

0.006

2.8733

2.2486

3.4981

M30–M36

22.77

0.002

2.6293

2.3203

2.9383

M30–M36

18.86

0.003

2.6672

2.2862

3.0482

M30–M36

11.40

0.008

2.5491

1.9591

3.1391

M36–M40

17.71

0.003

2.045

1.7657

2.3242

M36–M40

17.46

0.003

2.4692

2.1013

2.8372

M36–M40

15.41

0.004

3.4458

2.755

4.1365

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