Extended Data Fig. 1: Reactions catalysed by members of the thiolase superfamily and structures of corresponding enzymes. | Nature Catalysis

Extended Data Fig. 1: Reactions catalysed by members of the thiolase superfamily and structures of corresponding enzymes.

From: A polyketoacyl-CoA thiolase-dependent pathway for the synthesis of polyketide backbones

Extended Data Fig. 1

a, Reactions catalysed by members of the thiolase superfamily; (b) Three-dimensional structures of corresponding enzymes (monomer). The structures shown are those of Medicago sataiva chalcone synthase PKS III (1bi5), Streptomcyes albus ketosynthase domain of polyketide synthase KS/PKS I (4wky), Streptomyces coelicolor KS/PKS II (1tqy), E. coli β-ketoacyl-acyl-carrier-protein synthase KAS I (2vb8), E. coli KAS II (1kas), E. coli KAS III (1hn9), Arabidopsis thaliana KCS (modelling structure), human mitochondria thiolase I (4c2j), E. coli thiolase II (5f0v), and Bacillus subtilis HMGS (4yxq).

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