Table 2 Comparison of DDI prediction methods according to AUPR at different testing percentages.
From: Label Propagation Prediction of Drug-Drug Interactions Based on Clinical Side Effects
Methods | 15% | 25% | 50% | 75% | 85% |
|---|---|---|---|---|---|
NN-Chemical | 0.5182+/−0.0018 | 0.4932+/−0.0020 | 0.4067+/−0.0015 | 0.3810+/−0.0013 | 0.3667+/−0.0014 |
NN-LabelSE | 0.5537+/−0.0024 | 0.5137+/−0.0019 | 0.4549+/−0.0016 | 0.4038+/−0.0016 | 0.3791+/−0.0015 |
NN-OffLabelSE | 0.5780+/−0.0022 | 0.5412+/−0.0026 | 0.4710+/−0.0015 | 0.4331+/−0.0016 | 0.3924+/−0.0014 |
LP-Chemical | 0.6128+/−0.0040 | 0.6026+/−0.0026 | 0.5876+/−0.0016 | 0.5545+/−0.0022 | 0.4726+/−0.0025 |
LP-LabelSE | 0.6567+/−0.0035 | 0.6481+/−0.0021 | 0.6066+/−0.0019 | 0.5826+/−0.0023 | 0.5323+/−0.0028 |
LP-OffLabelSE | 0.7195+/−0.0031 | 0.7189+/−0.0019 | 0.6827+/−0.0022 | 0.6477+/−0.0026 | 0.6349+/−0.0031 |
LP-AllSim | 0.7292+/−0.0032 | 0.7282+/−0.0021 | 0.7052+/−0.0022 | 0.6736+/−0.0025 | 0.6501+/−0.0034 |
