Table 2 Mean pharmacokinetics parameters and bioequivalence results for Gamma Tocotrienol in 11 subjects after administration of GDT and TRF.

From: A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to existing Tocotrienol-Rich Fraction in healthy human subjects

PARAMETERS

GDT3

TRF

Tmax (h)

5.64 ± 1.50

4.73 ± 0.90

Cmax (μg/L)

8406.75 ± 3670.99

5604.67 ± 1971.73

AUC0–24 (μg/L*h)

39811.07 ± 13336.74 μg/L*h

23312.73 ± 9804.14

AUC0–∞ (μg/L*h)

41091.37 ± 13406.89

24256.29 ± 10591.03

Kel (1/h)

0.28 ± 0.12

0.31 ± 0.20

Half-life (h)

2.97 ± 1.31

3.45 ± 2.50