Table 4 Comparison of association status of SUA associated variants in healthy subjects and T2DM subjects.
Marker | CHR | BP | Nearest Gene | Al/A2 | Healthy Individuals | T2DM | Â | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
MAF (A1) | Effect size (95% CI) | p-value | MAF (A1) | Effect size (95% CI) | p-value | Cohen’s d | |||||
rs16890979 | 4 | 9922167 | SLC2A9 | A/G | 0.24 | −16.01 (−19.61–−12.41) | 2.62 × 10−18 | 0.23 | −23.20 (−32.58–−13.81) | 1.27 × 10−6 | −2.74 |
rs737267 | 4 | 9934744 | SLC2A9 | A/C | 0.27 | −14.45 (−17.91–−10.99) | 2.71 × 10−16 | 0.27 | −22.62 (−31.56–−13.68) | 7.07 × 10−7 | −3.26 |
rs2231142 | 4 | 89052323 | ABCG2 | A/C | 0.08 | 15.75 (10.01–21.50) | 7.82 × 10−8 | 0.08 | 22.83 (8.19–37.47) | 2.23 × 10−3 | 1.71 |