Figure 1: The western diet 5W80 induces obesity in mice. | Scientific Reports

Figure 1: The western diet 5W80 induces obesity in mice.

From: Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease

Figure 1

(A) Weight (grams, g) increases in male B6 and B6.APBTg after being fed a western diet (WD) for 8 months (p < 0.0001, n = 5) (B) Weight (g) also increases in female B6 and B6.APBTg after being fed a western diet for 8 months (p < 0.0001, n = 4). (C) Weight increased by approximately 20 grams in male B6 and B6.APBTg mice fed a western diet compared to mice fed the control chow (p < 0.0001, n = 5). (D) Weight increased by approximately 10 grams in female B6 and B6.APBTg mice fed a western diet compared to mice fed the control chow (p < 0.0001, n = 4). (E) Body fat percentage in WD-fed mice is significantly increased in both B6 and B6.APBTg male mice (p < 0.0001, n = 5). (F) Body fat percentage in WD-fed mice is significantly increased in both B6 and B6.APBTg female mice (p < 0.0001, n = 4). (G) Fasting blood glucose levels are increased in male B6 and B6.APBTg mice fed the western diet (p = 0.0072, n = 5). (H) Fasting blood glucose levels are increased in female B6 and B6.APBTg mice fed the western diet. Dotted line in (G, H) indicates diabetic blood glucose threshold. (p = 0.001, n = 4).

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